HTML5 Boilerplate
This template is a great starting point when creating a new website. The template contains jQuery, Modernizr, uses HTML5 tags and CSS3 also.
The template comes with and index.html page which should be base of all your pages in the site, it also has a 404.html page which can easily be changed to fit your sites theme.The template also handles using HTML5 tags in older tags with the aid of the Modernizr script.
Its definitely worth trying it out for any sites you need to create.